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Spring is here, and so is allergy season! Beyond the obvious pollen, mold spores thrive in damp environments, especially after seasonal rains, while dust mites multiply as temperatures rise. Pet dander also becomes a bigger problem as animals shed their winter coats.  

Meanwhile, grass pollens like Bermuda, Timothy and ryegrass kick into high gear in late spring, especially in May and June. These lightweight particles travel easily on the wind, making you miserable in your skin. 

For fast relief, many people turn to over-the-counter (OTC) antihistamines like cetirizine (Zyrtec) or loratadine (Claritin). Cetirizine works quickly but can cause drowsiness, so it should be taken at night, while loratadine is non-drowsy but may take slightly longer to kick in. Both block histamine, the chemical responsible for sneezing and itching.  

Nasal sprays like fluticasone (Flonase) reduce inflammation and congestion, but they take a few days to work and may cause nosebleeds if overused. This is effective for mild-to-moderate allergies, but if symptoms persist, you may need stronger support. 

If OTC meds aren’t cutting it, your doctor may prescribe montelukast (Singulair), which blocks leukotrienes, another inflammation trigger that your body makes when faced with pollen. It’s great for asthma-related allergies, but some people experience mood changes or vivid dreams. Ask your doctor about that one. 

Antihistamines come in two generations and a lot of people don’t know that. The first-generation meds (like diphenhydramine, or Benadryl) work fast but cause drowsiness. That’s why it got rebranded as a sleep aid! It’s great for nighttime relief but not for daytime function.  

The second-generation medications (like cetirizine, loratadine, and fexofenadine) provide longer-lasting, non-drowsy relief. They’re better for daily use but can still cause dryness or headaches. 

Some people live on these medications. However, you should know that taking antihistamines or steroid nasal sprays year-round can deplete essential nutrients — what I call the “drug mugging” effect. Here’s what to watch for: 

• Antihistamines can lower vitamin C and zinc, both crucial for immunity.
• Nasal steroids may reduce vitamin D, leading to weakened bones and increased infections.
• Montelukast can impact magnesium and B vitamins, affecting mood and energy.

If you rely on these meds daily, consider supplementing with what they deplete; your body will thank you. 

Natural remedies 

I love weaving in natural options for allergy relief. Consider the following:  

• Vitamin C acts as a natural antihistamine, reducing sneezing and itching.
• Vitamin D keeps your immune system balanced.
• B Complex helps regulate histamine and supports energy.
• Catalase helps detox oxidative stress, which can worsen allergy symptoms.

If OTC meds aren’t helping or your symptoms include wheezing, facial swelling or sinus infections (like sinus fungal balls, which I’ve written about before), it’s time to see a doctor. 

You don’t have to suffer all season! If you’re interested in a deeper dive into this topic, I’ve written a longer, more comprehensive article on my website, suzycohen.com. 

This information is opinion only. It is not intended to treat, cure or diagnose your condition. Consult with your doctor before using any new drug or supplement.   

Suzy Cohen is a registered pharmacist and author of The 24-Hour Pharmacist and Real Solutions from Head to Toe.